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The GetGoal programme established the efficacy and safety profile of lixisenatide 20 g once daily across the spectrum of patients with type 2 diabetes, including patients not treated with anti-diabetic agents, those failing on oral agents and as an adjunct to basal insulin therapy

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Reduced amounts of IL-10, which is produced by lymphocytes and macrophages, are associated with metabolic syndrome and inflammatory responses in individuals with T2D via the reduction of tyrosine kinase activity of insulin receptors [27]

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